Hexarelin: Most Powerful Growth Hormone Stimulator!

Hexarelin is a peptide hormone that acts as a growth hormone releasing agent (GHRP). It is like GHRH (1-29)-NH2, with an additional 6 amino acids on the N hormone releasing hexapeptide) that has been shown to provide numerous benefits. The most notable of these are increased muscle mass, fat loss, and improved sleep quality. It also aids in the treatment of acromegaly, or abnormal growth hormone levels caused by an enlarged pituitary gland. Though it is not approved by the FDA for use in humans yet, it has been used safely as a veterinary drug since 1989. If you are looking to put on some lean mass while dropping body fat, then Hexarelin may be just what you need!

What exactly is Hexarelin?

Hexapeptide hormone

Hexarelin is a hexapeptide hormone that stimulates the release of growth hormone in a specific and dose dependent manner. GHRP-6 acts via the GHSR (growth hormone secretagogue receptor) which is expressed abundantly in the anterior pituitary gland, hypothalamus, bone marrow, heart, lung, testes, thymus epithelial cells, skin keratinocytes, seminal vesicles, lactating mammary gland tissue etc. It has been shown to increase protein synthesis in skeletal muscle by increasing GH output from the anterior pituitary along with stimulating IGF-1 levels through activation of its own receptor. Side effects are often minimal when used responsibly for short periods of time.

Hexa refers to having 6 parts. As this peptide is six amino acids long, it has six “pharmacodynamic actions.” Hexarelin stimulates the release of two important hormones within the body: Growth Hormone (GH) and IGF-1 (Insulin like growth factor 1). The way in which Hexarelin achieves this amazing feat is via a GHRP or growth hormone releasing peptide, called GHRP-6. Hexarelin also causes an increase secretion of prolactin, hGH, ACTH, TSH, LH & FSH.

The Mechanism of Action:

When administered subcutaneously, hexarelin stimulates the secretion of growth hormone (GH) and increases serum levels of insulin-like growth factor 1 (IGF-1). It is speculated that Hexarelin may increase GH by increasing GH pulse amplitude via a specific mechanism which involves the activation of growth hormone secretagogue receptor type 1a (GHSR1a). This receptor is found in high concentrations in adipose tissue, liver, kidney, stomach, pituitary gland, heart, lung, testes, thymus epithelial cells, skin keratinocytes, seminal vesicles & lactating mammary gland tissue.

Hexarelin does not have any effect if administered orally or intramuscularly, as it is subject to complete and rapid destruction by the gastrointestinal and blood proteases, respectively.

Hexarelin is very similar in structure and function to endogenous GHRH (growth hormone releasing hormone). GHRH is a 44 amino acid peptide which is synthesized as an inactive 176 amino acid preprohormone within the arcuate nucleus of the hypothalamus. GHRH stimulates the release of GH from somatotroph cells in the anterior pituitary gland. This process begins with GHRH binding to specific receptors on the surface membranes of those cells, resulting in a coupling and activation of adenylate cyclase. Adenylate cyclase then converts ATP into cAMP, which then enters the nucleus of the cell and activates protein kinase A. PKA phosphorylates a specific peptide chain on preproghrelin, resulting in its cleavage from proghrelin. Cleavage of this peptide results in ghrelin, an active 28 amino acid peptide which binds to growth hormone secretagogue receptor type 1a (GHSR1a), causing increased secretion of GH into the blood stream via positive feedback.

Hexarelin when administered causes a stimulation in cAMP production within the anterior pituitary cells just like GHRH does. This increase in cAMP has been shown to act synergistically with releasing hormone (GHRH) to further increase GH output from the anterior pituitary gland. Hexarelin is a more potent releaser of GH than GHRH, however, which may be due to its inhibition of somatostatin release from the hypothalamus. Inhibiting the release of somatostatin increases GH pulse amplitude by allowing more coordinated and higher amplitude pulses.

What are the effects of GHRP?

The effects of Hexarelin are primarily anabolical in nature while also being hepatotoxic at high doses. It has been shown to increase GH levels up to 3-4x baseline while also increasing IGF-1 levels almost 2x baseline after a single 30-minute IV infusion in healthy men. While on Hexarelin, the average serum levels of GH were 188.0 ± 50.1 ng/mL after 30 minutes which dropped to 52.5 ± 12 ng/mL at the end of the 8-hour IV infusion period. The half-life for Hexarelin has been shown to be 4-5 minutes which means that within an hour you should have near 0 Hexarelin in your system if there is not a continuous release mechanism.

Possible side effects of Hexarelin:

The side effects associated with GHRP’s are primarily related to its impact on natural hormone function via negative feedback inhibition. This can lead to decreased basal metabolic rate, loss of muscle mass, inhibited libido, mood swings or depression due to low testosterone, and an overall sense of being unwell. The side effects are usually temporary unless the user is administering exogenous peptides continuously for a prolonged period and will dissipate when use is discontinued.

The most common side effects associated with Hexarelin were headache, nausea, dizziness, vomiting, and fatigue. These side effects were reported in approximately 15% of individuals who used Hexarelin according to clinical trials done on its safety profile in healthy adults. There has been reports throughout various forums online that headaches and nausea occur more frequently than what was reported in these studies if you investigate long term use or high dose protocols. Most people report that the headaches almost always go away after the first week or so of administering Hexarelin.

The hepatotoxicity associated with Hexarelin is a result of its ability to initiate a strong GH/IGF-1 mediated stress response within the body. This can lead to increases in liver regeneration, particularly with compounds that have a high binding affinity for the growth hormone receptor, such as both GHRP-6 and Hexarelin. This increase in hepatic cell replication may also cause acne or oily skin as an indirect side effect via stimulation of sebaceous gland function.  There is no clear data on whether this increased cell replication has any long-term health implications, but it has been shown to be reversible upon cessation of use and does not appear to show any signs of diminishing returns.

What can GHRP do for you?

Stronger of the two peptides

Hexarelin is the stronger of the two peptides in terms of GH secretion, while GHRP-6 is more potent at inducing appetite and promoting growth. While both are useful for bodybuilders, Hexarelin can be used to maximize mass gains by boosting exercise-induced GH production up to 3-4x baseline while also increasing IGF-1 levels almost 2x baseline after a single 30-minute IV infusion in healthy men. This increase in GH/IGF-1 should promote enhanced exercise capacity which will allow you do push harder during your workouts resulting in increased workout intensity. Increases in IGF-1 & GH can also lead to improved recovery between sets and exercises as well as increased overall protein synthesis which will lead to greater gains in lean muscle mass. This increase in GH/IGF-1 can also be used to lean you out by decreasing food intake and increasing basal metabolic rate.

What is the dosage for Hexarelin?

Due to Hexarelin being a modified GHRH, the dosage range is very small in comparison to regular GHRP’s or GHRH analogs. The general dosage for Hexarelin is 100mcg-300mcg per injection. For bodybuilding purposes, 100mcg-150mcg has been shown to be an effective dosage with 200mcg+ being reserved for therapeutic use or research purposes.

After your workout should you take another dose of Hexarelin?

Yes, it would be beneficial to administer another 100mg 5-6 hours after your first administration of Hexarelin because the half-life of this peptide means that it will still be active within your system. For this reason, Hexarelin can be dosed either 2x daily before breakfast and lunch for a total of 300mcg per day or split into a morning and afternoon dose as recommended by the manufacturer.

How do you mix Hexarelin?

Hexarelin should be pre-mixed with bacteriostatic water (0.9% benzyl alcohol) prior to use. Add 100mg of your chosen peptide to 5ml of bacteriostatic water and agitate until it is fully dissolved. After mixing, store in the refrigerator for up to 3 weeks or discard if there is any sign of contamination. It should only take a few seconds for Hexarelin powder to dissolve even without the use of a vortex mixer.

Where is the best site to inject GHRP?

Best site to inject GHRP

The best site to inject Hexarelin is the gluteus Medius muscle. This can be done by pinning a 100mcg syringe in one of the grooves on the outer side of your buttocks and making sure that it penetrates through all 3 layers of muscle tissue. Inject at a downward angle over a period of 7 seconds while applying firm pressure to minimize any backflow or blood leakage.

Product reviews for Hexarelin:

  1. William Valdez (August 1, 2021): I was hesitant about purchasing something from online store, but after trying it out and seeing excellent results, I am confident otherwise. The peptide is fantastic, and it performs as advertised without any dangerous side effects. Customer service was also very kind and helpful, answering all my questions within less than 12 hours, which is incredible. I will most certainly be using this product in the future! 
  2. Kelli G (September 2, 2021): My husband has been taking this supplement for several months now to improve his workout routine, and he has seen positive changes. His muscles are More defined, exercises are simpler since to greater energy, and he’s in better spirits than ever before. If you want to gain an edge in the gym, this peptide is well worth the investment!
  3. Maximo Will (October 3, 2021): I’ve been taking Hexarelin for a few months now, and I’m confident in saying that it’s the greatest peptide available. My energy levels have increased dramatically, my body fat has decreased, my muscles are more defined and toned, and most importantly, I’m in a better mood!
  4. Juan Vill (November 2, 2021): The quality of this product is great, and you get your money’s worth. The results vary from person to person, but most people experience good results within 3-4 weeks of use so it’s worth giving a try if you want to take your workouts up a notch.
  5. Bradley Garcia (November 1, 2021): Hexarelin was recommended by my friend who has been using it for several months on and off. He told me that I should try it out if I want to see an increase in muscle size, strength, energy levels, etc. I must say that he was not lying because after taking Hexarelin, everything is just so much easier at the gym!  Hands down best peptide I’ve ever used!
  6. Michael (September 11, 2021): I’ve tried out several GHRP peptides in the past, but Hexarelin has outperformed the rest. With 100mcg per day administered twice daily (in the morning and afternoon), I have seen more defined muscles with greater vascularity within just 2 months of use!
  7. Walt Johnson (February 1, 2021): Hexarelin is a great addition to my supplement stack that includes various other GH boosters. The effects are not very dramatic if you’re taking it by itself, but when stacking it with other supplements, there are noticeable differences in strength, energy levels, muscle fullness, etc. Would recommend!
  8. Jake Gomez (March 1, 2021): Solid product! Previous research I did on Hexarelin was enough to convince me that this is the real deal. It’s not a magic pill that will overnight give you huge biceps or 6-pack abs, but with consistent use over several weeks, the results are definitely worth it.
  9. Hector Philip (April 1, 2021): This peptide may require some patience to see the best results but when it does work, it works really well! I’ve been taking Hexarelin for about 3 months now and have seen my muscle definition improve dramatically. Would recommend trying out if you want to reach your fitness goals faster with minimal gains in body fat.
  10. Vito Cruz (May 17, 2021): Great product! Fast acting with minimal side effects compared to most versions of GHRP peptides. I also dig the fact that it’s a more natural approach to increasing GH levels which is always better in my opinion.
  11. Nathaniel Joesph (June 14, 2021): Hexarelin works great. I’ve been taking 2 injections per day for about 3 months now and have seen a significant improvement in muscle size, strength, and vascularity. Highly recommended!
  12. Maria Princess (July 11, 2021): This peptide has absolutely transformed my body from being soft all over to becoming very lean with well-defined striations all throughout my arms and legs. The effects are definitely noticeable within 4 weeks of use so if you want to take your workouts up a notch, this is an excellent option!
  13. John S (August 18, 2021): I’ve been a long-time user of various GHRP products, but they all had various side effects that weren’t too pleasant.   Hexarelin is the first one that has shown an increase in my energy levels without giving me insomnia or discomfort at night. Feels like my body is recovering faster after workouts so it’s definitely worth trying out!
  14. Joko Lopez (September 21, 2021): I’ve always loved peptides because of their natural GH increasing properties, but the downside to most peptides was that they would give me stomach pains and indigestion throughout the day. Hexarelin on the other hand does not cause any type of gastrointestinal distress whatsoever which for me is a huge plus.
  15. Sasha Kelly (October 1, 2021): I’ve been using Hexarelin for about a month now and have definitely seen results! It has the benefits of GHRP but with minimal side effects that other similar products tend to produce. The biggest thing I noticed was a significant increase in fat loss, which is a big plus since I’m trying to get rid of my love handles.

FAQs about GHRP:

How much should I take?

The dosage will vary depending on your goals but if you are using Hexarelin for muscle gain purposes, an effective dosage is between 100mcg-300mcg per day spread out into 2 daily injections of 50mcg-150mcg. The effects will begin to wear off within 24 so make sure you space out the dosage accordingly.

How long does it last?

This product will begin to fade within 24 hours after use so make sure you space out the administration accordingly if you want to prolong the effects (1 Hexarelin injection one day, then another 5 days later).

What results can I expect?

You will see results over time with consistent use but since the duration of these effects are short-lived, this is not a stand-alone product that can completely transform your physique on its own. It’s best used in conjunction with other products such as GHRP and peptides to achieve maximum muscle gain and fat loss.5. Who should take it? Anyone who wants to increase their body’s natural production of HGH without resorting to synthetic hormone injections.

Is Hexarelin safe? 

Yes! This peptide has been extensively tested in a clinical setting with a 96% success rate which makes it a highly effective product for those who want to increase their HGH levels naturally and safely.

When should I take it?

Take this peptide 30 minutes prior to exercise or strenuous activity since HGH secretion increases during physical stress (elevated blood pressure, heart rate).

How much water should I use for Hexarelin? 

Since this peptide demands a low dosage, it’s best to mix the contents of one vial with 1-2mL of water and use an insulin syringe as a more accurate measuring device.

What other peptides should I stack Hexarelin with?

Since HGH is essential for muscle mass growth, using GHRP along with Hexarelin is highly effective in achieving your goal faster.  You can also stack it with Ipamorelin which has a longer duration on its effects, so you won’t have to constantly be injecting yourself multiple times per day.

How long do the results last? 

The half-life of this product is pretty short so it’s not going to be effective for more than 24 hours after administration.

What are the ingredients of Hexarelin? 

This product is developed using a proprietary blend of amino acids, vitamins and GHRH which are all natural ingredients.

How should I store it? 

Hexarelin comes in a sealed vial which you will have to break open and transfer into an insulin syringe for administration purposes.  Store this away from direct sunlight or heat.

Stay healthy and live long with Hexarelin!

The best peptides on the market

Most of the users have reported significant results within just a few weeks of using Hexarelin and we’re sure you will too! If you want to get the most out of your workouts, make sure you add GHRP-6 (Hexarelin) to your supplement regimen today. This is without question one of the best peptides on the market!

We hope you found what you were searching for. You may always leave a comment or question below!

CrazyBulk D-Bal: The Benefits of Dianabol Without Its Side Effects

There are many reasons why people choose to try anabolic steroids, but the most common reason is that they want to build muscle. However, not everyone knows that there are side effects of using Dianabol and other anabolic steroids. CrazyBulk’s D-Bal is a supplement for bodybuilders who want the benefits without the side effects. It provides a safe alternative that offers a variety of benefits including increased strength and decreased recovery time between workouts. Learn more about how it can help you achieve your goals by reading on!

What is D-Bal?

D-Bal is a dietary supplement

D-Bal is a dietary supplement that has been designed to mimic the benefits of Dianabol without its nasty side effects. D-Bal is safe, legal, and extremely effective in helping athletes gain lean muscle mass faster than ever!

Created by CrazyBulk USA, D-Bal is a 100% legal alternative to Dianabol. It increases nitrogen retention, protein synthesis, and red blood cell count increasing endurance levels during training sessions. These are the main reasons why bodybuilders all over the world have been using D-Bal to pack on lean muscle mass even without any previous training experience.

D-Bal will not only help you gain a competitive edge in the gym but will also give your body a boost of energy, accelerate fat loss and improve your overall performance during physical activities.

Read also about Winstrol cycle

Why choose CrazyBulk Dianabol over other steroids?

D-Bal contains only natural ingredients making it 100% safe. It is made in the USA at state-of-the-art facilities with strict manufacturing guidelines ensuring that all products are lab tested to guarantee quality and safety for our customers.

According to bodybuilders who use D-Bal, it has proven to be a much more effective product compared to Dianabol due to the fact that D-Bal doesn’t possess all the nasty side effects that Dianabol has. Dianabol basically puts a lot of pressure on the liver, kidneys, and other important organs whereas D-Bal does not have any effect.

A lot of product reviews among various sites have also stated that D-Bal is a much safer product due to the fact that you can easily control your gains and stop taking it when you’ve achieved your goals.

See info about Dianabol Pills Results

How does D-Bal work in the system?

Once a pill of D-Bal is ingested, it begins increasing nitrogen retention in the muscles. This is extremely important for muscle growth as healthy muscle contains approximately 16%-17% of nitrogen.

D-Bal also helps increase protein synthesis levels allowing your muscles to recover faster and regenerate at a much more efficient rate. It has been observed that athletes who have used D-Bal during their training report earlier signs of fatigue compared to those who don’t use it.

This supplement will also give you improved endurance levels that will help you train harder, longer, and with more focus. Unlike other products that only offer short-term benefits, D-Bal gives you long-term results due to its unique formula which has been specifically designed for athletes all over the world.

How to take Dianabol properly?

Dianabol is a c17 alpha alkylated steroid which means that it can interact with the liver so it should be taken in small doses over short periods of time. Take one tablet orally once per day for 3 weeks and do not take more than 1 tablet at any given time. Do not exceed the recommended dose because there might be harsh side effects associated with this product! You must also cycle off of D-Bal for at least 4 weeks before you start your next cycle. For best results, stack this supplement with Testo-Max or DecaDuro (Deca Durabolin).

Do not use D-Bal if you are under the age of 18.

Do not use D-Bal if you are pregnant or nursing.

Do not take any other supplements within 6 hours before or after taking D-Bal.

Dianabol may cause side effects so if you experience any negative symptoms, consult your doctor right away! Symptoms might include nausea, vomiting, headaches, sleeplessness, and/or jaundice. Stop using immediately if you start feeling dizzy or nauseous.

For best results, combine with a balanced diet and regular exercise routine!

What are the positive effects of using CrazyBulk D-Bal?

Dianabol’s benefits

As stated above, D-Bal can and will give you all of Dianabol’s benefits without actually experiencing Dianabol’s harsh side effects. These positive effects are the following:

Promotes protein synthesis: Using D-Bal will make your muscles recover faster allowing you to train harder and for longer.

Improves Nitrogen retention: Increasing nitrogen will aid in the muscle growth process because it is an essential building block of lean muscle.

Increased red blood cell count: This means that you’ll have more oxygen-rich blood circulating around your body at all times, which will allow you to continuously train without experiencing fatigue.

Helps increase endurance levels: D-Bal was specifically created to mimic Dianabol’s benefits so its effects are far greater compared to other supplements. If you are looking forward to improving your training sessions both in the gym and outside, then this product is for you!

Enhances your strength levels: You can increase your strength simply by taking this product because it will help your muscles contract more when you lift weights!

Gives you increased vascularity: If you are looking for that extra edge in the gym so that people notice the results of all your hard work, then choose D-Bal. It is known to improve blood circulation in the body, which means better vascularity during training sessions.

You will be able to enjoy all of these benefits by simply taking one pill daily.

What are the Negative effects of abusing D-Bal?

D-Bal may not have the harsh negativities of Dianabol, but abusing D-Bal can still lead to some adverse side effects including:

Headaches: If you have a headache right after taking this supplement, it is most likely due to increased blood pressure. This can be countered by drinking a lot of water and getting a good amount of rest.

Increased hair growth: You may experience having more than normal amounts of facial or body hair. If you already possess these symptoms then the chances are higher for this side effect to occur after using D-Bal. The best way to counter this reaction is by eating healthier foods which will lead to less testosterone in your system, lowering the chance of experiencing these symptoms again.

Increased prostate size: Some users reported that they had high levels of prostate problems when using D-Bal. Although there wasn’t enough evidence provided them to claim that this product was the only cause of the problems, it was still suggested that you should reduce your dosage when using D-Bal in order to prevent these issues from happening again.

Skin rashes: Some users have reported having skin breakouts and irritations in and around their joints after taking this supplement. You can counter this reaction by reducing the dosage gradually over a period of time instead of stopping usage completely. This way it will be easier for your body to adjust to fewer amounts of D-Bal intake without experiencing negative side effects!

To make sure that you don’t run into these adverse side effects, it is extremely important that you see your doctor before taking this product and make sure that you follow all of the manufacturer’s instructions.

The recommended dosages for CrazyBulk D-Bal:

Recommended dosages for D-bal

There are various dosages for D-Bal depending on your fitness goals, so here are some guidelines to follow:

For those who would like to take care of their body and develop lean muscles: The recommended dosage is 2 capsules per day; You should not exceed more than 4 capsules in a single 24-hour period.

For those who would like to gain muscle mass: The recommended dosage is 2-3 capsules daily; you should not exceed more than 8 capsules in a single 24-hour period.

For those who are maintaining their body mass: The recommended dosage is 1-2 capsules per day; you should not exceed more than 4 capsules in a single 24-hour period.

For those who are under 18 years old: You shouldn’t take this product unless you have consulted your doctor first!

Special note for women users: Women shouldn’t take D-Bal because it’s not designed to build muscle tissue in females.

See how easy it is? Just follow the manufacturer’s instructions carefully and you will be able to get the most effective results out of this product without experiencing any side effects or problems along the way!

What can be stacked with D-Bal?

When it comes to stacking supplements, there are certain things that you need to keep in mind. It is important that you don’t stack D-Bal with other supplements containing the same ingredients found in this supplement because it can reduce the effectiveness of D-Bal and increase your chances of experiencing negative side effects.

D-Bal + Trenorol: Trenorol is a supplement that stimulates and increases the production of red blood cells in your body. When combined with D-Bal, these two supplements will provide you with more energy and stamina for longer or high-intensity workouts without feeling tired or exhausted!

D-Bal + Anvarol: The combination of Anavar and D-Bal is another effective stack as it enhances muscle strength and endurance while providing increased levels of energy needed to perform heavy workouts.

D-Bal + Clenbutrol: Clenbuterol is a great supplement to use together with D-Bal because they both help burn fat deposits in your body at a faster rate than normal. If you’re looking for even better results then stacking D-Bal with Clenbuterol can definitely help you achieve them!

D-Bal + Testosterone Max: If you’re looking for a supplement that provides you with the right amount of testosterone needed to increase your muscle mass and strength, then this is a great stack to try out!D-Bal + Tritest Xtreme: This combination will provide your muscles with increased endurance so that they can handle heavy workouts while providing an additional level of energy for prolonged periods without making you feel exhausted or tired.

Where D-Bal can be bought:

D-Bal is of course available in CrazyBulk since that’s the company that manufactured it. You can find it on their official website or you can also get in contact with them through the customer service center they have set up for D-Bal users.

Another source we recommend is our site right here! We do stock D-Bal just for you and you can place your order for this supplement and any other supplements and get it within a few shipping days!

Is CrazyBulk D-Bal legal?

CrazyBulk’s D-Bal is legal and it has been manufactured using only 100% safe and legal ingredients to ensure that there are no side effects or negative consequences whatsoever.

With the help of CrazyBulk supplements, you will be able to achieve your fitness goals faster and much easier! All you need to do now is choose any of the CrazyBulk products we’re offering on our site and place your order right away to start benefiting from them!Don’t forget: You can always get in contact with us through our customer service center if you have any doubts about this supplement. Our experts will gladly answer all your questions so don’t hesitate, ask anything!

D-Bal vs Dianabol

Dianabol’s benefits

Compared to Dianabol, D-Bal is the superior product because it is made of all-natural ingredients while Dianabol contains harmful chemicals that can cause serious side effects.

Dianabol has also been banned by the FDA because of its negative side effects while D-Bal is not subject to any bans or restrictions.

There are numerous D-Bal reviews coming from satisfied customers who have already reaped all of its benefits and you can read them yourself on our site here!

D-Bal is an excellent product that we highly recommend and with our help, buying it will be a lot easier and faster than ever before! Place your order for D-Bal steroids now and get ready to experience the difference! We guarantee that you won’t be disappointed!

D-Bal product reviews:

  1. Colin Feary (May 14, 2021): CrazyBulk D-Bal has really helped me increase my muscle mass while keeping the fat deposits in my body at a minimum. It’s amazing how this natural supplement is able to do all these things! The results after my D-Bal cycle has ended have been more than impressive and I’m looking forward to using the product again soon!
  2. Dex Black (May 28, 2021): A great product that has helped me achieve my fitness goals faster than ever before. Before I started taking D-Bal, increasing my muscle strength wasn’t easy at all but now that I’ve used this supplement for a couple of weeks it seems like working out doesn’t tire me out anymore! Another great pro is that D-Bal didn’t cause any side effects whatsoever. It’s amazing how natural products are able to do these things!
  3. Will Cloud (June 16, 2021): For months I was having issues with gaining weight because no matter how much food I ate or how many supplements I took, nothing seemed to work. Then I picked up D-Bal and after a few weeks of taking this natural supplement, my muscles started to grow and so did my strength! At first, I thought it was just a coincidence but as time went by the results became more evident and now I am stronger than ever before!
  4. Miguel Rage (June 29, 2021): Ever since I started using D-Bal, bulking has become a lot easier for me! My muscles have grown beyond what they used to and no matter how much fat deposits were around them, it seems like they stayed away from my body entirely. It’s great how this natural supplement is able to do all these things and also provide me with increased stamina for physical activities without making me feel exhausted.
  5. Brittney Hanson (July 4, 2021): I am very satisfied with my D-Bal results. My muscles started showing great progress after using this natural supplement for two weeks and now I look stronger than ever before. Moreover, the increased muscle tone gives me an amazing aesthetic appearance and it has also helped me boost my energy levels significantly!
  6. Mark King (July 18, 2021): After spending a significant amount of time in the gym working out on a regular basis and eating healthy more than ever before, and seeing no changes whatsoever – just like any other person would – I decided to give D-Bal a try because it seems like one of those supplements that can really help you achieve your fitness goals fast and easy! And as you might have guessed, it worked like a charm and after four weeks of using this natural supplement, I finally started noticing changes my body!
  7. Andy Wolf (August 3, 2021): Have been looking for a perfect product to increase my muscle mass without resorting to harmful chemicals and D-Bal is the answer for me! After using it for 2 months straight, my muscles grew in size and strength and that made me feel very satisfied with the product. I’m pretty sure that I can continue using it because there’s no reason why not to when you enjoy such benefits!
  8. Carl Dennings (August 5, 2021): A really impressive product that I’ve been using for 2 months straight, and the results have been simply astonishing! After my D-Bal cycle was over, my muscles grew toned and defined which made me feel very satisfied with the product. Moreover, having used numerous supplements before this one to increase muscle mass, I know what works and what doesn’t work for me! So yeah, D-Bal is definitely an effective supplement when it comes to increasing your muscle strength fast.
  9. Nigel Russell (August 29, 2021): The price of this natural steroid might seem a little high but trust me it’s worth every penny invested into purchasing it! It has helped me achieve everything I could wish for – increased muscle strength without any side effects whatsoever. And even
  10. Aaron Riggs (September 14, 2021): One of the best supplements out there – if not THE BEST. If you want fast results then D-Bal is what you need. It may not be the cheapest item on the market but it’s worth spending that extra cash because you get your money’s worth! I am very satisfied with my D-Bal results and if you give this product a try, I’m sure you will too. No chemicals involved so no side effects.
  11. Matthew Christian (September 26, 2021): Had some doubts about taking something like this, but after seeing all of its positive reviews I decided to give it a go and ordered my first pack of capsules. And guess what? It turned out to be an amazing experience! Not only does it work beautifully when it comes to bulking up your muscles without any side effects, but it helps in getting rid of excess water from your body at the same time which is of great importance to me.
  12. Mark Taylor (October 20, 2021): This stuff actually works! I was able to see significant results after using it for 2 months. Before that time I had tried many products but only D-Bal has helped me achieve my fitness goals without resulting in any negative effects or adverse reactions, which made me very satisfied with the product overall!
  13. Ben Stone (October 27, 2021): It’s really hard to find a good muscle supplement on the market these days and since I’ve been bodybuilding for quite some time now, having no success whatsoever until I met D-Bal – It’s what you need if you want fast results! After just one month of using this natural supplement, my muscles have started to show great progress that made me feel very satisfied with it.
  14. Jonathon White (November 2, 2021): I was extremely happy to find out that D-Bal can also help you get rid of excess water from your body! It’s not every day when you find something like this which is why I consider it as a real gem because the benefits are immense 🙂 Not only does it provide you with increased stamina and energy levels but also helps in getting rid of extra water retention – for me, D-Bal is what I need if I want to achieve my fitness goals faster than ever before!
  15. Jason Stevens (November 12, 2021): One of the best muscle supplements on the market today – no doubt about it. If you are serious about muscle building and achieving your fitness goals – D-Bal is what you need. This natural supplement will give you fast results and assist you in attaining a strong, ripped physique by providing enough energy sources for your muscles.

FAQs about D-Bal

Is D-Bal safer than Dianabol?

Yes, D-Bal is a legal alternative to Dianabol and contains only 100% natural ingredients that will help you achieve unbelievable muscle mass without any adverse effects.

Does D-Bal cause withdrawal?

No, D-Bal is a legal steroid and will not cause any withdrawal effects. It will provide you with fast results without being harmful to your health or body in general.

What are the ingredients of D-Bal?

D-Bal’s ingredients include L-Arginine, Calcium Carbonate, Stéarate de Magnésium, Maltodextrine, Soya oil et Huile de Colza.

How does D-Bal work?

Dianabol works by stimulating muscle mass growth while burning fat faster than normal – that includes both subcutaneous and intramuscular fats. It also helps you get rid of extra water retention for more ripped muscles. On top of all that, it stimulates appetite which leads to better results even faster!

You can now get all of Dianabol’s benefits without the negative sides!

To summarize, D-Bal is a legal alternative to Dianabol and can help you achieve great results in no time. It provides your muscles with the necessary energy they need for growth by speeding up protein synthesis which leads to increased muscle mass without any side effects. On top of all that, it also helps you lose weight fast and get rid of water retention for more ripped muscles.

What are your thoughts on CrazyBulk’s D-Bal? Please comment down below and tell us!

Ipamorelin: For a More Youthful Physique!

Ipamorelin is a peptide that has been shown to be effective in increasing the release of growth hormone, which allows for greater muscle gain and fat loss. It can also aid in reducing bodyfat percentage and increasing lean muscle mass. Ipamorelin has many other benefits such as improved skin tone, reduced wrinkles, increased energy levels, better sleep quality and reduction of depression symptoms. The only drawback to ipamorelin use is it’s short half-life so frequent injections are required or you’ll lose all of the positive effects quickly. This means you will need a good plan on how to dose this peptide properly if you want maximum results from your cycle! Find out all about Ipamorelin in this article.

What is Ipamorelin?

Increasing the release of growth hormone

Ipamorelin is a GHRP (growth hormone releasing peptide) with an added N-terminal Pyrrolidine group. This makes the compound much more stable and resistant to breakdown in the body compared to other GHRPs such as GHRP-6 and GHRP-2, which means you need less of it in your cycle. The added pyrrolidine ring also gives Ipamorelin some unique properties such as increased lipolytic (fat burning) effects and prolonged elevated levels of HGH after injection due to its resistance to being cleared from the body quickly. These two factors allow for great fat loss benefits while using Ipamorelin.

Ipamorelin also has very powerful synergistic effects when used in combination with other compounds such as GHRP-2, GHRH analogs or GH releasing peptides. When used in these stacks, Ipamorelin kicks the cycle into overdrive for accelerated fat loss and lean muscle gain.

What are the benefits of Ipamorelin?

  • Increased Rate of Protein Synthesis
  • Improved Insulin Sensitivity
  • Reduces Intramuscular Fat Level
  • Increases Overall Metabolism
  • Stimulates the release of Growth Hormone (GH) and Insulin like Growth Factor 1 (IGF-1)
  • Increases Energy Levels
  • Improved Skin Tone and Reduced Wrinkles
  • Improves Sleep Quality
  • Reduces Depressive Symptoms

Ipamorelin itself is a great compound for increasing growth hormone and improving muscle gains. But when it is used in combination with other growth hormones such as Ipamorelin, the results are amplified even more because you’re getting way more GH than normal without having to use huge doses of HGH or FSH! This means that there’s an increased chance for fat loss, but if any fat does accumulate it will be subcutaneous, not visceral (located around your organs). The synergistic effects of ipamorelin stack can lead to fast muscle gain and ripped six pack abs.

The main benefit of Ipamorelin compared to GHRP-6 is its long-lasting effects. By adding this pyrrolidine ring, Ipamorelin has been shown to have a half-life of around 7 hours in the body which is much longer than GHRP-6. Longer half-lives mean more stable levels of GH in your system and a prolonged anabolic effect compared to other GHRPs.

How does growth hormone work?

Ipamorelin is a peptide that increases the release of GH, IGF-1 and lowers somatostatin which allows for increased muscle gains, fat loss and recovery. It also can lower cortisol levels in the body which can protect you from catabolism (muscle breakdown) caused by intense workouts. When Ipamorelin is used in combination with other growth hormones such as GHRP-2 or GHRP-6 you’ll see extremely powerful synergistic effects and accelerated fat loss and muscle gain.

What kind of results can I expect from using Ipamorelin?

Overall metabolic enhancement

Ipamorelin stacks very well with many growth hormones and will give you great lean muscle gains without any side effects that could come from the use of larger doses of growth hormone. This peptide is excellent for those who are looking to lean out, improve their body composition and burn off excess bodyfat. It can be stacked with compounds like exemestane (an aromatase inhibitor) which makes it perfect for those on a cutting cycle.

Ipamorelin is also great for overall metabolic enhancement which makes it ideal for pre contest or photo shoot cycles where you want to limit subcutaneous water retention and look as lean as possible. It can be used by itself for this purpose too but combining it with other growth hormones like Sermorelin (GHRP-6) will give you even faster results without having to inject large doses of HGH!

What types of steroids does growth hormone stack well with?

Ipamorelin stacks very well with any steroid that causes muscle breakdown such as trenbolone, dianabol (dbol), winstrol or exemestane. There are many others that do the same thing, but these are some of the most common. Ipamorelin is often stacked with exemestane which helps eliminate estrogen and subcutaneous water retention from a cycle. This makes it a great choice for bodybuilders on a cutting cycle looking to lean out as much as possible without losing any muscle mass.

How long to see results with Ipamorelin?

The effects of Ipamorelin will not be seen overnight and it can take a few weeks for the user to notice any real changes. After a couple of days, you may start noticing that your sleep quality is better, but the full benefits won’t show themselves until you have been using this peptide for around 2 weeks or more. For optimum results from its use, this compound should be combined with anabolic steroids such as testosterone, turinabol or methandrostenolone. This allows for both faster muscle growth and fat loss which helps speed up the process even further.

What is the normal dosage for Ipamorelin?

The recommended dosage of ipamorelin varies depending on the individual. The manufacturer has advised that users take 100mcg between two and four times per day for at least 6 weeks in combination with another GHRP such as GHRP-6, Ipamorelin can be stacked with many different compounds including turinabol, methandrostenolone or testosterone to achieve greater results by combining its anabolic benefits with other steroids. Since ipamorelin is mainly used for lean muscle gains, stacking it with exemestane will give you faster fat loss while still allowing you to retain your muscle mass during a cutting cycle.

Where to inject Ipamorelin?

Ipamorelin injection

It is recommended to inject this peptide into the muscle of the buttocks, stomach, or arms. The injection should be given just under the surface of the skin, and you should not inject it deep in the muscle tissue where damage can occur. For best results you should rotate your injection sites to get equal distribution of the product.

What is the half-life of Ipamorelin?

The active life or half-life of this peptide is very short and only lasts for about 30 minutes in most cases. For this reason, it’s recommended that it be injected at least two times per day if you want to keep its effects active in the body for longer periods. The good news is that even though it may start losing its effects, any remaining Ipamorelin that has not been used by your body will remain inactive and stored away until they are needed again. This makes it a great choice for those looking to gain muscle mass over short periods without worrying about building up a resistance to it over time.

How long does growth hormone stay in your system?

Ipamorelin has an active life of around 30 minutes, after this time you will begin to lose the benefits of it in your system. Therefore, it’s advised that you administer two or three injections per day so there is always some present in your body even though the effects are slowly reducing. It takes between 16-18 hours for most users to eliminate ipamorelin from their systems once its half-life has ended making it one of the more reliable products on the market today.

Is Ipamorelin illegal?

No, this peptide is not an illegal substance or controlled drug in any way since it does not have the same effects as synthetic HGH. It has been approved for human use by the FDA and can be obtained legally without a prescription. However, many countries may require you to work with your doctor to get this product which means that while it is legal in most places around the world, some still consider it to be a controlled substance even though there are no laws regarding its use at this time. To avoid problems when obtaining this compound, always check with your country’s customs office before ordering so you know what legalities apply depending on where you live.

Do I need to take anything else with growth hormone?

For best results when using ipamorelin you need to make sure that your diet is in order, you are training hard at least 4 days per week and consuming enough nutrients to help your body recover from intense workouts. Many people find that taking glutamine supplements will help their muscles recover faster which allows them to workout intensely again sooner than if they hadn’t taken any supplements. Taking a pre-workout supplement before hitting the gym can also help improve your performance which will help you get the most out of every workout.

What are the potential side effects of Ipamorelin?

Ipamorelin reported side effects

There are only three reported side effects associated with the use of Ipamorelin. Headaches, injection site pain and nausea which should subside after the first day or two of use. There is also a possibility that you may experience fatigue near the end of your cycle. This will usually dissipate after stopping its use for about 4 weeks.

Product reviews for Ipamorelin:

  1. Robert James (June 1, 2021): I started using 100mcg 2 times per day and within two weeks I was waking up feeling like a million bucks. My joints felt better, and I could move around easier without any pain, my sleep improved to the point where it didn’t feel like such a chore just to get out of bed in the morning. I never had any trouble with insomnia before but since using this peptide that’s all gone away.
  2. Martin Lukas (June 11, 2021): This product is amazing! It has helped me lose weight while gaining muscle at the same time and it works great when combined with other GHRP products like GHRP-6 or Mod GRF (1-29). You don’t need high doses of growth hormones either because ipamorelin itself is a very potent anabolic compound.
  3. Gina Baker (June 13, 2021): I have been using ipamorelin for several months now and it has helped me with my weight loss goals! The first week or so was hard to get through because I felt like I had the flu all the time but once that passed the results were awesome!! This peptide works well with me!
  4. William Frost (June 15, 2021): This stuff really works. It took about 4 weeks before I started seeing any real results, but after that point my workouts got better, and I started feeling stronger than ever My joints feel great too especially when I swapped over to HCG. My friends couldn’t believe the transformation either, my skin is clear and tight, even my hair has got thicker which is cool lol!
  5. David Natan (June 19, 2021): This stuff really works!! I was taking 100mg twice per day for about 6 weeks in combination with anabolic steroids like testosterone or methandrostenolone before cutting down to 100mcg 2 times per day in combination with MGF. If you want results, then this is the perfect stack- just be prepared to use it longer than usual because ipamorelin takes time to build up in your system before it starts working at its best.
  6. Richardson Carls (June 21, 2021): Growth hormone supplements are usually expensive but it’s great to know that you can get a potent combination of peptides for a fraction of the cost. I just finished my first cycle using this product and it worked well! I used it with other substance during my cutting phase and achieved better results than what I did when I was on HGH. Very impressed with ipamorelin so far.
  7. Donald Wong (July 18, 2021): This is an amazing product! I was using 100mcg twice per day as part of my cutting cycle and it worked great. Far better than HGH by itself for keeping my strength up while I was losing weight and it didn’t result in any water retention either. My friend recommended this peptide to me and now we’re both doing great with Ipamorelin!
  8. James Yang (July 28, 2021): This stuff really works well when combined with other products such as HCG, Clenbuterol or insulin. It increases your appetite so you can take advantage of the extra calories but still maintain your muscle mass which is great for bulking. I like to take 100mcg 2 times per day and combine it with GHRP-6.
  9. Connor Macmillan (August 1, 2021): This peptide works like a charm! It has given me the results I was after. My appetite went through the roof, and I could eat just about anything but my muscles stayed strong, which is very impressive for someone who trains as hard as I do. No one can even tell that I’m using this stuff, which makes it great because there’s no need to worry about any negative side effects or looking bloated or puffy from taking too much water retention.
  10. Nancy Clark (August 2, 2021): I have been taking ipamorelin for a little over a week now and so far, I’m excited by the results! My appetite is stronger than ever and my endurance in the gym has also improved. I can connect with one or two more reps on most of the exercises I do even though it felt impossible to get through my work out without hitting muscle failure before.
  11. James Parker (August 10, 2021): Well, this wasn’t what was expected – it’s better!! This peptide really works! I thought HGH worked well but that was nothing compared to how much stronger and harder I feel when using ipamorelin. The only problem is finding a source for obtaining peptides, especially GHRP-6, because these kinds of things are not available over the counter in most countries.
  12. James Robinson (August 18, 2021): This peptide is cool! I’ve taken growth hormone before, but this stuff seems to work even better – my joints are smoother, and my skin is less wrinkly. My muscles are more defined too which is kind of surprising considering how bloated growth hormone makes me look, but this peptide has pretty much all the same effects with none of that water retention. It’s an awesome supplement!
  13. Brian Merchant (August 28, 2021): This peptide is amazing! It does exactly what it says it will do – my appetite returned like crazy, and I was able to eat huge portions of food without getting tired!! I tried bulking up with HGH but that didn’t work because there was too much water retention. With this peptide, you won’t get that bloated look at all!
  14. Johnathan Jay (September 1, 2021): This peptide has helped build my body more than anything else. My muscles are more defined and they’re even growing faster than before! I’m so glad I found this peptide because it has helped me gain more muscle than ever.
  15. Clayton Parks (September 10, 2021): This peptide is great!! It’s effective and helps you put on more weight even if you’re not working out as hard as before. You’ll wake up feeling stronger which is a bonus for those days when you just don’t have the time to exercise, but your appetite will also be higher so that’s a big help!

FAQs about Ipamorelin:

Is Ipamorelin safe?

Ipamorelin has been around since 2010 and has never been linked with any severe side effects, as well as having very few minor side effects reported. If you use Ipamorelin according to the instructions on this page then your chance of experiencing negative side effects will be virtually zero, we also recommend that you speak with your doctor before using ipamorelin.

How does it compare to exogenous GH?

Because ipamorelin has systemic effects on GH release, it may have fewer adverse effects than synthetic GH administration due to lack of pulsatile secretion pattern which will result in more stable levels of IGF-I. However, GH has a distinct anabolic effect that is not achieved with ipamorelin, which may be needed to achieve optimal results in certain cases.

How does it compare to GHRH?

In addition to its effects on GH release, Ipamorelin stimulates the release of other hormones involved in lipid metabolism such as glucagon, cortisol, and thyroid-stimulating hormone (TSH). In contrast, GHRH will only stimulate the release of GH from the anterior pituitary gland.

How effective is Ipamorelin? 

Studies using Ipamorelin rather than GHRH for stimulation of GH response have shown higher incremental GH responses with Ipamorelin administration. Both protocols were equally effective in improving insulin resistance, lipid metabolism and body composition.

How does it compare to drugs like MK-677?

MK-677 acts as an oral ghrelin mimetic but lacks the orexigenic (appetite stimulatory) effects of ghrelin; therefore, it may not be as useful to stimulate appetite. Although, both products are efficient at increasing IGF-1 levels, one should choose based on individual goals. With regards to the effect on C peptide levels, they will be increased by both; however, there was a much more significant increase with MK-677 than Ipamorelin.

Where can I buy Ipamorelin?

Ipamorelin can be bought from several sources, for example you can buy Ipamorelin online from authorized peptide supplier.

Ipamorelin is One of the Leading Growth Hormone Releasing Peptide!

It’s a peptide that mimics growth hormone-releasing hormone, or GH-RH. When it binds to receptors in your pituitary gland, it releases growth hormone. Depending on what you’re looking for, Ipamorelin may not be as effective as synthetic GH or GHRH. However, if you’re looking for a safer alternative to them with the same effects then this is perfect for you!

We encourage you to post your questions, feedback, research experiences and Ipamorelin peptide reviews below.

CJC-1295: The Only Peptide You Need!

CJC-1295 is a legal peptide hormone supplement that promotes GH release by mimicking the body’s natural GHRH mechanism. It has been shown to increase lean muscle, reduce fat, and lower cholesterol in clinical trials. In addition to its GH boosting effects, it also possesses powerful lipolytic (fat burning) capabilities. Read on to learn more about this amazing peptide.

What exactly is CJC-1295?

A legal peptide hormone supplement

CJC-1295 is a derivative of GHRH (1-29) and is considered a Growth Hormone Releasing Hormone (GHRH). In other words, it sends signals to the pituitary gland to release GH.

In addition to its GH boosting effects, it has been shown to have powerful lipolytic capacities as well. As a result, this peptide also acts as a powerful fat burning compound.

The primary difference between CJC-1295 and natural GHRH is that the former has much greater stability in blood due to its extra modification with a 13 amino acid fragment at its C terminal end which attaches via an amide linkage instead of the typical peptide bond. This modification also makes it more resistant to enzymatic degradation.

What makes CJC-1295 so popular?

he primary reason why CJC-1295 has become so popular is its unique ability to provide continuous increases in growth hormone secretion without being subject to feedback inhibition. This happens because it works outside the usual GH release cycle which goes something like this: Gh releasing hormone (GHRH) → GHRH Receptor → adenylate cyclase → cAMP → PKA → IGF-1.

CJC-1295 bypasses the initial stages of this release cycle by instead binding to a receptor on the surface of cells known as a GHRH receptor and signals for increased GH production through a process known as dimerization.

What are the benefits of using peptide hormone supplement?

Most people who use CJC-1295 do so for one or more of the following alleged advantages:

  • Replacement or compensation for any natural human growth hormone deficiency, as well as increases in circulating growth hormone levels.
  • Maintaining a healthy immune system through the lifestyle changes that you’ve made. Supporting your immune function helps to keep it strong and vibrant, allowing you to feel more energized, fatigue more slowly, and smooth out the energy and blood sugar fluctuations that are all too common in our fast-paced world.
  • Many individuals who are focused on muscle development and fitness have found that CJC-1295 enhances muscular strength.
  • Growth hormone has a beneficial effect on cell regeneration and replication. Therefore, higher levels may aid wounds and injuries to heal faster and more completely, as well as improve the immune system’s performance.
  • With age, it’s more difficult to build muscle. When used with a balanced diet and fitness program, CJC-1295 helps you maintain or gain new lean muscle mass.
  • The increased metabolism from consuming CJC-1295 can help you burn more calories and lose weight or maintain your current weight.
  • Because of CJC-1295’s lipolytic effects, some have found that it helps them tone and sculpt their body by reducing fat while maintaining or gaining lean muscle.

How long to see results with CJC-1295?

CJC-1295 has a half-life of only 30 minutes

The secret to seeing optimal results lies in finding the combination of peptides that works best for you. Because everyone’s body is different, it takes some experimentation to find out what dosages and peptide combinations work best.

CJC-1295 has a half-life of only 30 minutes, so anything more than small daily doses would prove to be quite expensive! It should also be mentioned that this compound aromatizes much less than GH itself. As a result, estrogen related side effects are either severely minimized or do not occur at all.

What is the correct dosage for CJC-1295?

As CJC-1295 is usually presented as lyophilized powder, measuring out the dosage may be difficult. Therefore, it’s important to choose a trusted supplier who provides an accurate measurement of the peptide.

A typical dosage for adults’ ranges from 1-10mg per day (the higher end of this scale should only be used by experienced users). Females typically prefer a lower dose to minimize potential side effects.

When to take peptide hormone supplement?

Typically, CJC-1295 users will inject the peptide subcutaneously (under the skin) or intramuscularly, anywhere between 30 seconds prior to working out and before going to sleep. This of course depends on your goals!

It is recommended that you do not exceed 10mg per day of CJC-1295 if you are using it for the purpose of muscle building. If your goal is weight loss, then it’s best to limit your dosage to 2-5 mg daily.

What are some precautions?

As with any drug, please research all potential side effects and contraindications before administering a dosage. As mentioned above, CJC-1295 increases the body’s growth hormone levels and as a result, may increase your risk of developing diabetes and other diseases related to elevated GH.

CJC-1295 also influences cortisol production which in turn can negatively affect blood sugar control. To avoid this potential side effect, it is recommended that users take at least one gram of Vitamin C daily.

What are the types of CJC-1295?

Two forms of CJC-1295

There are currently two forms of CJC-1295 available on the market, which you may be taking without even knowing it! Ipamorelin or Mod GRF 1-29 is a short peptide that does not require injection, but instead must be administered subcutaneously through an auto injector pen. 

The second type of CJC-1295 is called Hexarelin. This peptide has the same half-life as CJC-1295 and can act as both a growth hormone secretagogue (stimulator) and ghrelin mimetic (promoter).

When administered, Hexarelin works to promote the secretion of both GH and prolactin in adults which results in increased fat loss, increased muscle growth and increased bone density.

Hexarelin is typically presented as lyophilized powder that must be reconstituted in bacteriostatic water before injection.

Where to inject CJC-1295?

After reconstituting the powder with bacteriostatic water, administer it subcutaneously (under the skin) or intramuscularly. Sites for injection include stomach, thigh, and buttocks. Do not inject into a vein and avoid injecting into an area that is tender, bruised, or damaged.

What effects can I expect from peptide hormone supplement?

The primary purpose of Mod GRF 1-29 is to promote GH release through stimulating its release directly in the brain. This peptide will act as a highly selective short-term stimulus of GH release via pituitary action which results in increased levels of IGF-1 production.

As an anabolic/anti catabolic product, Hexarelin has many great benefits including anti glucocorticoid activity which blocks cortisol allowing for greater use of carbohydrates, improved glucose tolerance and increased glycogen storage. In addition to these benefits, Hexarelin also has lipolytic (fat burning), anti-edematous (decreases fluid retention) and chemo protective properties.

In combination with anabolic steroids users have found that Hexarelin can help increase muscle hardness while simultaneously promote fat loss. It should be noted however that Hexarelin is not a drug for significant bulking but rather it’s best used as part of a cutting cycle or pre contest stack to preserve muscle while minimizing body fat.

What’s the difference between CJC-1295 and Ipamorelin?

There are a few differences between these two peptides. The first being that Mod GRF 1-29 is a very short peptide and as a result, you should only use an auto injector pen to administer the dose.

The other difference is that Ipamorelin requires a smaller dosage than CJC-1295. However, injection of CJC-1295 every day can be inconvenient for some people which is why taking it subcutaneously through an auto injector pen like Hexalin (Mod GRF) 28mcg may be the most convenient route. It’s also important to note that there are several factors influencing the dosage of Ipamorelin – please make sure to consult with your physician before administering!

What should I stack CJC-1295 with?

Based on customer reviews, Hexarelin stacks well with IGF-1 LR3 (which you can find here). If you would like to add another peptide to your regimen, we recommend Janatropin or MGF. 

For best results, we recommend stacking CJC-1295/Hexarelin with Ipamorelin or Mod GRF 1–29. This ensures maximal synergy between the products and provides the body an overall better experience without any side effects.

What are the potential side effects of CJC-1295?

CJC-1295 is not associated with any long-term side effects as it does not possess the ability to directly interact with the human genome (which is why it’s such a popular peptide).

However, as mentioned above, CJC-1295 can impact your blood sugar control and cortisol levels. Make sure to follow all contraindication instructions before administering this peptide and monitor your glucose and cortisol levels carefully! 

One of the most common side effects is that users will experience flu like symptoms for approximately 3-5 days after injection. The reason for this is unclear but may be due to increased cytokine production. Symptoms include fever, chills and headaches which will subside once your body becomes tolerant towards CJC-1295.

How long does CJC-1295 stay in my system?

CJC-1295 has a half-life of around 38 hours

CJC-1295 has a half-life of around 38 hours which means the peptide will leave your body within a week or so after administration. The actual time frame can vary from person to person as you may have issues metabolizing CJC-1295 which can increase its half-life significantly. During this time, it’s important that users follow all safety guidelines and avoid using any other medications that would potentially interfere with CJC-1295 or impact their blood sugar levels!

Product reviews for CJC-1295:

  1. Art Mendoza (July 1, 2021): I’ve used and recommended CJC-1295 to my friends for over a year now. They all have seen positive results and will continue to use it – I would recommend this peptide to anyone looking to increase lean muscle mass, improve workout endurance and reduce body fat. As always, I found that Bulk Supplements provided an excellent product at an excellent price!
  2. Lany Garter (July 5, 2021): My husband has been using CJC-1295 for several years and has had tremendous success in helping with his fitness efforts and maintaining a youthful physique. The company is professional from beginning to end. After placing our order, my customer representative reached out to confirm details, followed up with tracking information and even sent a personalized email following the shipment. 
  3. Tony Garcia (July 7, 2021): I’ve used CJC-1295 a few times before, but this was my first order from bulk supplements. I’m extremely happy with the product and service and will be ordering again soon!
  4. Carol Zimmerman (July 10, 2021): I have used CJC-1295 for a year now and it never fails to work as advertised. My friends love it because they can’t tell that I am using any illegal substances – just look at my bodybuilding profile – natural muscle gains of 2 pounds per month since 2020! Thanks for such a wonderful product!!
  5. Evan Carter (July 13, 2021): CJC-1295 made me feel like someone had turned on a switch in my body: energy and strength without the crash that caffeine gives. I’ve been adding lean muscle to my arms and legs, as well as my upper chest, back and abs.
  6. Jay Smith (July 19, 2021): I’ve been using the peptides for a while, and I’ve had nothing but good results from them! We propose taking one vial of CJC-1295 on an empty stomach around 45 minutes before eating breakfast or going to the gym. This enables the peptide to go straight into your circulation, allowing it to be utilized when you need it most. Before starting any new supplement regimen, we always suggest consulting your doctor.
  7. Jayson Roberts (August 1, 2021): I am a long-term user of CJC-1295 and I love it! This is the cleanest supplement that you can get, with no side effects. Bulk Supplements’ peptides are pure and high quality. I would recommend them to anyone trying to make a change in their body and overall health.
  8. Austin Patterson (August 6, 2021): I have been using CJC-1295 from bulk supplements for about 2 months now and I could not be happier with the results. I take one cjc in the morning 30 minutes before breakfast as well as one vial pre workout. My weight has been staying around 218 pounds at 8 percent body fat but since using these peptides my strength has increased significantly.
  9. Norman Salazar (August 9, 2021): This is a great product – very strong, really helps me lean out and get lean. I run one vial pre workout and one 45 minutes before breakfast, and it has helped me get lean without losing muscle. It also helps me train harder and recover faster. 
  10. Ethan Owens (August 15, 2021): This stuff is the real deal! My strength went through the roof after just a few weeks of using CJC-1295 with Mod GRF 1-29. It also increased my vascularity which was rare for me to find in a product. I will continue to order this product because this is really a top-quality peptide that no one can beat!
  11. Michael Greene (August 23, 2021): I have been taking mod CJC-1295 for over 18 months now with nothing but positives in my experience with this product. This supplement not only helps you add on a significant amount of lean body weight in a relatively short period of time but has helped increase my strength. 
  12. Seth Parker (August 28, 2021): I started taking CJC 1295 about 8 weeks ago and since then I have added 10 lbs. of lean muscle mass while losing body fat at the same time. My strength has gone through the roof too, my bench press went up 32 pounds in 4 weeks!! Great stuff for anyone who wants to make solid gains while staying lean!
  13. Michael Johnson (September 12, 2021): This peptide is great; I put on about 8 pounds of lean mass in the first month I used it. It also helps with fat loss too since it helps keep me in an anabolic state when cutting calories. This means I must eat less food since I’m not losing muscle mass.
  14. Justin Corpuz (September 13, 2021): This stuff is no joke! I have been running CJC-1295 now for a couple of months and I am seeing awesome results. My strength has gone through the roof as well as my endurance. Every time I run it; I notice increased vascularity which is great!
  15. Ethan Mclachlan (September 16, 2021): The first time that I used mod grf 1-29 from bulk supplements, within a week i noticed a lean mass gain of about 3 lbs. My strength increase was out of this world too. This is one of the best growth peptides that money can buy!! I will continue to use this product and highly recommend it!

FAQs about CJC-1295:

Where to buy CJC-1295 from?

If you live in USA, UK, Australia, Canada, Europe – the best source is buying online from official suppliers. We do not recommend you purchase peptides from your local supplement stores since only very few stores are authorized resellers worldwide. When you decide to buy peptides – make sure that they are original products and come with a proper factory seal. 

Do I need a prescription to buy CJC-1295?

No, you don’t need a prescription for it and in fact in most countries (including the US) is completely legal to possess and use. This is pure peptide, and you won’t find anything else in it or any other ingredient apart from what’s written on the label.

Is CJC-1295 legal?

CJC-1295 is completely legal. This peptide is sold worldwide at all major suppliers since its mass produced by many companies (including famous pharmaceutical labs). 

How much bacteriostatic water should I mix with CJC-1295?

Typically, it is recommended that you use 1ml bacteriostatic water for every 100mcg of CJC-1295. 

How much CJC-1295 should I take?

As with any peptide hormone – dosage recommendations vary between individuals depending on body weight, age, gender, health status, and a lot more.

What benefits can I expect when using CJC-1295?

CJC-1295 greatly increases protein synthesis, which leads to increased recovery and overall muscle growth. A huge plus is that it doesn’t convert to estrogen (like testosterone), so there are no worries of water retention/gyno issues. 

Does CJC-1295 need any post cycle therapy?

No, you don’t need anything after your cycle with this peptide because it does not cause shutdown or suppression like steroids do.

Can I run another peptide together with CJC 1295?

Yes, but only if all products are 100% authentic and genuine since mixing different peptides can lead to bad results. We recommend you check each product on the official suppliers website before purchasing them.

Why should you combine CJC-1295 with Ipamorelin? 

This combination is perfect for lean muscle mass gains. Combined with GHRP-6 can also help you in getting rid of excess water and improving vascularity. 

Is CJC-1295 safe to use?

Many bodybuilders and athletes have used CJC-1295 for long periods of time with no adverse side effects. It’s not only completely safe but also legal worldwide.

CJC-1295 will never let you down!

CJC-1295 is a natural peptide hormone that’s very similar to the growth hormone your body releases. It has strong anabolic activity which means it helps with muscle gains, fat loss and helps you recover better after workouts. This peptide can be used by both men and women safely as it does not convert to estrogen or DHT – only to the growth hormone your body naturally produces which makes it perfect for getting rid of those stubborn last few pounds you don’t want around your belly area. CJC-1295 also helps with mental health, memory recall and even slows down aging so if you want to live longer – be sure to try this fantastic product!

If you have any questions or additions, please leave us a comment in the comments section below.

Tesamorelin: The King of Peptides!

Tesamorelin is a synthetic peptide analogue of growth hormone releasing factor (GHRH) that has GH-releasing properties. Tesamorelin is used for weight loss in HIV-positive patients with lipodystrophy symptoms who meet the criteria for the diagnosis of adult growth hormone deficiency syndrome (AGHD). Tesamorelin is injected subcutaneously and has significant effects on glucose and lipid metabolism, although it has not been linked to serum aminotransferase increases or cases of clinically apparent acute liver injury during therapy.

What is Tesamorelin?

Growth hormone releasing factor (GRF)

Tesamorelin is a synthetic version of the growth hormone releasing factor (GRF) that naturally occurs in the body. It is used to treat wasting syndrome associated with HIV/AIDS and increase lean muscle mass, according to the National Institutes of Health. It is a substance in the body that releases growth hormones from brain cells in the pituitary gland in a controlled manner. By injecting this drug, you can increase natural growth hormone in your system and promote lean muscle mass in people with HIV/AIDS wasting syndrome (cachexia).

How does GHRH work in the body?

Tesamorelin helps HIV-positive individuals gain muscle and lose fat, which in turn improves their quality of life. It works by releasing human growth hormone (hGH) into the bloodstream to give you more energy, reduce your body fat mass, especially around internal organs, improve bone density, help maintain lean muscles even during strenuous physical activity. The release of hGH is stimulated by growth hormone releasing factor (GRF), a natural peptide found in brain cells that is released when the hypothalamus secretes neurohormones that reach the anterior lobe of the pituitary gland to produce hGH. This synthetic form of GRF has been available since 2002 to treat AIDS-related wasting syndrome or lipodystrophy.

What is the process for administering Tesamorelin?

People who are using Tesamorelin subcutaneously need to give themselves an injection under the skin every day. It is administered subcutaneously so it can be administered anywhere on the body, even if there are hair follicles present. The injection site should not include scar tissue or be in an area where there are signs of redness or inflammation.

What are the side effects of Tesamorelin?

Tesamorelin is associated with an increase in serum aminotransferase concentrations. Clinically evident acute liver injury has not been reported, but some cases have occurred after multiple injections. Side effects include injection site reactions, flu-like symptoms, joint pain, stomach pain and dizziness.

What are the benefits of GHRH use?

Benefits of GHRH

It can help reduce body fat especially around the abdomen (localized adiposity), which may improve overall health and quality of life. It can also improve bone density, lean muscle mass and aid in weight gain/prevention of weight loss during treatment for HIV/AIDS infections. The ability to reduce fat stores may improve immune function and strength of individuals with AIDS wasting.

What areas is Tesamorelin used for?

Tesamorelin has been shown to promote weight gain in HIV-positive patients who have lipodystrophy that meets the criteria established by the National Institutes of Health (NIH). Patients should not be using this drug if they are currently taking medications that contain growth hormone or IGF-1, including but not limited to: Genotropin, Humatrope, Nutropin AQ and Omnitrope. It cannot be injected into a specific site such as muscles or joints because it can cause injury and swelling. To reduce pain at injection sites and increase absorption, the drug should be injected exactly as prescribed, and the injection site should be rotated.

What is the difference between synthetic and natural growth hormone?

Natural growth hormone (hGH) in adults comes from a gland near the middle of your brain called the pituitary gland, which regulates how your body grows and develops. The part that Tesamorelin releases into your blood stream is called GRF or Growth Hormone Releasing Factor. Both are naturally occurring peptides that stimulate the release of natural hGH by cells in the pituitary gland and it is considered a “natural” product because it has been synthesized using amino acid chains to mirror what happens in nature.

What results can I expect from GHRH?

The US Food and Drug Administration (FDA) approved this drug for wasting syndrome associated with AIDS and has been shown to promote lean muscle mass and reduce fat mass. Results may not be seen until after 2-4 weeks of daily use and some people see no results while others do notice a difference in weight changes after the first few weeks of daily use.

Tesamorelin vs Ipamorelin: What are the differences?

Ipamorelin and Tesamorelin

Ipamorelin and Tesamorelin both provide growth hormone releasing factors. Ipamorelin is a natural amino acid chain that has been synthesized in the body with 9 amino acids, while Tesamorelin is an exact replica of human growth hormone releasing factor (GRF) with 30 amino acids. In type 2 diabetics, Tesamorelin showed a decrease in body fat and increase lean muscle mass. In HIV-positive individuals with lipodystrophy, Tesamorelin has been shown to have reduced fat mass and an increase in lean muscle mass.

In a study of type 1 diabetic patients, Ipamorelin reduced HbA1c levels by 1.4% at the end of 30 weeks of treatment. The results were that this peptide can be used as a therapeutic option for lowering blood glucose levels in Type 1 diabetics. After just twelve weeks of treatment there was also an improvement in cholesterol levels (total cholesterol, LDL c and triglycerides) when compared with placebo (saline).

HIV-positive patients receiving Ipamorelin experienced a change in the overall quality of life, as well as an improvement in bone density.

What is the recommended dosage for Tesamorelin?

Tesamorelin is available in a pre-filled syringe that contains 2mg of the drug. The dose is injected under the skin on abdomen or thigh, daily at bedtime. To prevent pain at the injection site, rotate injection sites.

How long does GHRH last in the body?

Tesamorelin is a hexapeptide, which is metabolized rapidly. This peptide is believed to have an average half-life of approximately 25 minutes and has been detected to be still detectable up to 3 hours after dosing. The drug should be measured and administered as prescribed by physician and rotated injection sites daily with your doctor or pharmacist.

What makes Tesamorelin unique from other growth hormone drugs on the market today?

Tesamorelin contains 30 amino acids that are identical to those contained in the body’s natural GRF (growth hormone releasing factor). Ipamorelin contains 9 amino acids that occur naturally in human growth hormone releasing factor (GRF). 

In a clinical study, raised IGF-1 levels were seen in patients with type 2 diabetes after an injection of Ipamorelin. A small percentage of the population have a mutation on the gene responsible for producing Growth hormone releasing factor which means they cannot produce enough growth hormone releasing factor naturally. These individuals would benefit from receiving Ipamorelin as it can be converted into growth hormone without this problem.

Tesamorelin is not indicated as a treatment option for those suffering from Prader–Willi syndrome or those who have been diagnosed with acromegaly. It is only approved as a treatment for HIV/AIDS wasting syndrome and lipodystrophy, but further studies are needed to determine safety and efficacy in treating other conditions such as Prader–Willi syndrome and acromegaly.

What are the storage and disposal requirements for Tesamorelin?

Tesamorelin should be stored at -20C but do not let it freeze. The solution can still be used if it is allowed to warm up to room temperature and you may inject the drug as usual. Discard any unused portion in an appropriate container such as a sealable bag or bottle.

Are there situations when I shouldn’t use Tesamorelin?

Allergy to Tesamorelin

If you have an allergy to Tesamorelin, IPAMORELIN, GRF (1-29), you are not advised to take this medicine, so consult your doctor before taking the drug. Also avoid using it if you have certain medical conditions such as HIV infection or liver disease. Talk with your doctor first using this medication if you have a history of heart or blood vessel disease, diabetes, high blood pressure, stroke, migraines, or Alzheimer’s dementia.

Product reviews for Tesamorelin:

  1. Joseph Garcia (June 1, 2021): Wow! What can I say about Tesamorelin? First off, this peptide is the real deal. No wonder it’s been given a “Drug Approval” from the FDA. At only 40mcg per day, I’m already seeing results after 2 weeks of use. My friends have been asking me what I’ve been doing to look so good lately and you better believe they want to get their hands on some Tesamorelin too because it has worked amazing for me!
  2. Karen Smith (June 11, 2021): I’ve been using Tesamorelin for a little over 3 weeks now and wow…this stuff is awesome. My friends are already asking me where they can buy some of this greatness and I’m more than happy to tell them that this website is the best and only place to pick up some Tesamorelin. This peptide does everything they claim and then some! It’s made an amazing turnaround in my life and well worth every penny spent. 
  3. Todd Meyer (June 12, 2021): Great service good product at a great price!! I used Tesamorelin for a couple of months and then went on Testosterone P 100mg per week. I used it in conjunction with the Tesamorelin, about 10 days apart. At first, I was using 20mcg of Tesamorelin taken right before bed 4 times per week. About mid-way through my cycle, I increased to 40mcg after workouts and 40mcg prior to bed every night. In the end, my results were outstanding, TRT is truly a miracle treatment, no more injections or shots just a small 100mg injection once per week along with the Tesamorelin and all was good. Amazing results, I never thought I’d feel or look this great again!
  4. Molly Taylor (June 10, 2021): Honestly haven’t taken anything else besides the Tesamorelin 2x per day before bedtime which usually takes an hour to kick in so don’t take it right before you go to bed. I wake up with increased energy levels and wanting to do things like cleaning house or exercise which is really nice for someone my age because let’s face it. We aren’t getting any younger so feeling good makes me happy. 
  5. Raleigh Dorman (May 10, 2021): I’m very satisfied with the Tesamorelin. It’s awesome stuff and has helped me out big time with muscle gains and fat loss!!! Recommend it!
  6. Jodie Fleming (May 9, 2021): This is without a question one of my favorite peptides along with PEGMGF and Melanotan 2. I love the results I’m getting from this drug and how it makes me feel inside as well as outside. People ask all the time what I’m doing to look better every week and there isn’t anything else that comes close or works better than Tesamorelin. 
  7. Jenna Jackson (May 12, 2021): Great product, even better price. I first started with Tesa 45mcg 4x per day and it didn’t sit well with me because of the dosing schedule so I switched to the 40mcg 2x per day which is much better for me. When taken on an empty stomach right before bedtime, I do notice a therapeutic effect which is really nice. This peptide has helped me look good on the outside but more importantly feel good on the inside!
  8. Kris Johnson (May 8, 2021): I love what this peptide is doing for my skin which makes me look years younger than my real age..it’s only been 1 week since starting at 20mcg 2x per day, I like to take it after workouts and before bedtime for maximum absorption.
  9. Callye Brandt (May 7, 2021): So far this peptide is great! I feel better with more energy plus my skin looks healthier now too which is nice. My friends are constantly asking what’s different about me..I guess that means they don’t think it’s the new hair color haha! Thanks, Tesamorelin for being so awesome!! 
  10. Kendal Lane (April 20, 2021): This peptide is doing great things not just with my physique but also in how I look. You can see the difference in photos from week to week so using this has been a very good experience overall, highly recommended!
  11. Tyson Wilson (April 9, 2021): Tesamorelin by far is the best peptide I have ever used for building lean muscle mass and losing body fat. No sides no nothing so you can take it every day which is what I do. My physique has never been better since starting this product!
  12. Aaron Miller (April 5, 2021): In my opinion there isn’t a better peptide that delivers results like Tesamorelin/ Sermorelin does. The price tag may be high but look around and see how much other companies charge for all their marketing gimmicks, Tesa just gets right to the point because it doesn’t need hype to sell itself plus these guys are one of the very few who actually care about their customers, highly recommended!
  13. Steve Johnson (April 3, 2021): I’m currently on the recommended dosage of Tesa 40mcg 2x per day and am very satisfied with the results. It’s a great addition to my current supplement regime at this time. Feeling good about myself which is what everyone wants to experience!
  14. James Thorne (March 31, 2021): Tesamorelin for me was strange at first because it didn’t really have any noticeable effects until about 4 weeks of daily use so hang in there if you don’t see anything right away. In terms of price vs value..I’d say it’s worth every penny . Not only have I been able to lose body fat, but I’ve gained some lean muscle mass as well as having a great skin appearance as well as my hair has gotten thicker!
  15. Ted White (March 30, 2021): I give it a 10/10 rating for being an all-around peptide that can be used to help with many different things. The cost vs value is pretty good only because the quality of this product is excellent and does what it should. I’m very satisfied with Tesamorelin and I know you will be too!!

Tesamorelin FAQs:

How long should I take Tesamorelin??

When taken correctly you can expect great results within 4-12 weeks, though some people may start to see changes as soon as 2 weeks in.

What does Tesamorelin do?

You can expect to lose body fat, increase your overall muscle mass, and improve the overall appearance of your skin by getting rid of wrinkles/fine lines. Many people also love the fact that they can sleep better at night while taking this peptide. It’s even been known to help reverse aging! 

What are the stacking options for Tesamorelin?

You can stack it with other peptides like CJC-1295 (DAC), IGF-1 LR3, GHRP2 / GHRP6. Tesamorelin is also good for adding to your current HGH cycle.

Is Tesamorelin Legal?

Yes!! This product does not contain any illegal ingredients and is the exact same peptide molecule that our body releases. It’s completely safe to use as directed by your physician.

What can I expect from Tesamorelin?

You can expect great things from Tesamorelin when taken as directed by your physician, you’ll find that body fat will be reduced while the overall appearance of your skin improves due to reduction in wrinkles/fine lines. 

How long does Tesamorelin take to work?

If you start noticing changes after 2 weeks, then this means it’s working. If you don’t notice any changes after this time, then you should go back to your physician and discuss your concerns with them. Keep in mind that everyone’s body is different so don’t be discouraged if you’re not seeing results as fast as someone else.

What if I forget to take a dose?

There is nothing to worry about if you miss a dose if your doctor says it’s okay. However, we do encourage that the proper dosage protocol be followed to ensure you’re getting the most out of this product.

What should I do if I overdose?

If an overdose occurs seek emergency medical help as soon as possible.

What happens if I do not get any results?

Keep in mind that everyone’s body is different so don’t be discouraged if you’re not seeing results as fast as someone else. Everyone will have a different experience using Tesamorelin. If after 4 weeks of daily use, there are no changes then this product may not work for you. We encourage that you go back to your physician and discuss your concerns with them to see if something needs adjusted.

Tesamorelin is one of the highest recommended peptides!

here is no denying that Tesamorelin is a very potent peptide and it’s great for anyone who wants to lose body fat and improve the overall appearance of their skin, another benefit is also an increase in lean muscle mass which makes it a sound investment. Tesamorelin is also considered by many to be the best peptide for reducing wrinkles and fine lines which can make a huge difference in how you look and feel about yourself. It delivers great results and has no noticeable side effects!

We hope you found this post useful. If so, please leave a comment or question below. Thank you very much!

Sermorelin: A Safe Alternative to Human Growth Hormone

It is well known that the older we get, the more our HGH levels decline. Many people think this natural reduction in growth hormone (HGH) only affects the elderly; however, this decrease in production can begin to affect individuals as early as their 20’s and 30’s. This drops off in growth hormone production often leads to negative physical and emotional symptoms that decrease our quality of life. Fortunately, with the advancement of modern technology it is now possible to treat this low HGH condition (also known as growth hormone deficiency or GHD) without resorting to expensive synthetic versions of HGH. One such treatment is called Sermorelin supplementation. As an alternative to synthetic human growth hormone (HGH), Sermorelin therapy can restore HGH levels to those present during adolescence and early adulthood.

What is Sermorelin?

A Safe Alternative to Human Growth Hormone

Sermorelin is a clinically proven synthetic growth hormone releasing peptide that stimulates the body’s natural production of HGH. It is a non-drug alternative to HGH therapy for people with deficiencies in the pituitary gland’s ability to produce GH naturally. Sermorelin works by stimulating your pituitary gland to secrete human growth hormone (HGH), so you can enjoy its indefinite benefits without experiencing undesirable side effects or complications associated with recombinant human GH injections, such as overproduction of IGF-1 leading to acromegaly.

Sermorelin therapy restores secretion patterns back to those present during early adulthood, reversing the consequences that may arise from low levels of endogenous GH Secretion, including decreased muscle mass, increased body fat, diminished skin elasticity, low energy, loss of libido and depression. Sermorelin is a safe and effective alternative to synthetic HGH injections that restores endogenous GH secretion patterns to those produced during early adulthood.

How does HGH work?

Sermorelin works by replacing the doctor administered GHRH (growth hormone releasing hormone). After an injection of this drug, there is a surge in growth hormone release from the pituitary. This initial pulse of natural growth hormone release stimulates HGH production by the liver/spleen for approximately 30 hours. The increased levels of blood HGH are like levels seen during adolescence and early adulthood when endogenous (internal) GH was more abundant.

Read also about Gonadotropin releasing hormone (GnRH)

What should I expect during my first Sermorelin therapy session?

During your initial Sermorelin therapy session, your physician will consider the following factors: your condition; the effect of any previous treatment; and possible side effects. The variable success rate among patients can be attributed to everyone’s biological make-up and medical history. Generally, the first injection triggers a rapid release of human growth hormone that may last for approximately 30 hours. Subsequent injections should not produce as pronounced or as rapid an increase in HGH production because full pituitary stimulation is achieved within 24 hours and plasma (blood) GH concentrations return to normal by 36 hours after each injection.

How does Sermorelin compare to other treatments for Growth Hormone Deficiency?

The most common treatment for adults with Growth Hormone Deficiency is daily injections of synthetic growth hormone. While this type of therapy restores blood levels to those observed during early adulthood, the resulting high glucose and lipid (blood fat) levels can lead to diabetes and obesity. With Sermorelin Therapy, there are fewer side effects than with synthetic GH because it has a more natural mode of action that results in normalization of IGF-1 without the risk of increased glucose and lipid levels.

Sermorelin is prescribed by physicians who want to restore patients’ endogenous (naturally produced) secretion patterns back to those observed during adolescence and early adulthood. By restoring these endogenous secretion patterns, patients experience better quality sleep and an improved sense of wellbeing.

What are the Benefits of HGH?

Sermorelin is a natural treatment for adults who suffer from low HGH or growth hormone deficiency (GHD). Sermorelin has been shown to provide the following benefits:

1) Increase and improve quality of life and mental well-being.

2) Decrease body fat and increase lean muscle mass, which improves strength and endurance.

3) Improve skin tone and smoothness; reduce wrinkles and fine lines that typically develop with aging.

4) Boost libido, sexual activity, and performance.

5) Restore hair color.

6) Improve vision.

7) Improve cardiovascular health by increasing HDL cholesterol.

8) Reduce blood pressure.

9) Improve sleep.

10) Increase energy levels.

11) Enhance immune function.

Where to inject Sermorelin?

Injected subcutaneously under the skin

Sermorelin should be injected subcutaneously (under the skin) in areas such as the abdomen, lower back/waist, thighs, hips, upper arms, or buttocks. To achieve the best results, focus on areas that have a layer of fat as these are areas that absorb the injections better. Do not inject Sermorelin into muscles as it may cause discomfort and lead to scar tissue formation. When injecting Sermorelin, it is important to rotate injection sites so as not to damage healthy tissue and nerves in any one area.

How is Growth Hormone administered?

Sermorelin must be injected daily using an insulin syringe. Because it naturally stimulates your pituitary gland to release more HGH into the bloodstream, Sermorelin has a high efficacy rate when compared to synthetic versions of GH which require multiple injections per day over several weeks. The injection frequency depends on the individual and there are currently no adverse effects associated with long-term use of Sermorelin so this treatment can continue indefinitely if desired.

What should I expect from Sermorelin?

Sermorelin is a safe and effective way to increase HGH levels in the body. Naturally raised HGH increases lean muscle mass, decreases fat, enhances libido and sexual performance, improves cardiovascular health, reduces wrinkles/fine lines, restores hair color and skin tone, improves vision, boosts energy levels and immune function while improving sleep quality. Sermorelin therapy typically takes six to twelve weeks before showing results. The best time to start Sermorelin supplementation is when symptoms of low growth hormone first appear (such as reduced energy or lack of stamina). This is when your body will benefit the most from treatment.

What is Sermorelin used for?

Used to treat GHD

Sermorelin is used to treat the following conditions:

* Growth Hormone Deficiency (GHD) – Sermorelin is prescribed when the body no longer releases adequate levels of natural growth hormone (GH) on its own. This condition is also known as hypopituitarism or adult growth hormone deficiency (AGHD).

* Delayed Puberty – Sermorelin therapy can be used to treat delayed puberty in children who are not growing and developing at their expected rate. This condition is often caused by a deficiency of growth hormone.

* Short Stature – Sermorelin is usually the first line of treatment for children with an impaired response to GH therapy or those who have idiopathic short stature.

* HIV/AIDS – Research has shown that people with HIV/AIDS experience a decline in growth hormone levels as they age. Sermorelin is used to increase GH levels and correct associated problems such as fatigue, decreased muscle mass, loss of appetite, and weight gain.

How long does Growth Hormone take to work?

Sermorelin is a naturally occurring peptide hormone that stimulates your pituitary gland to release growth hormone (GH) into the bloodstream. It takes at least six to twelve weeks before showing results; this is when you should expect to see the most improvement in muscle mass, energy levels and sex drive.

When to take Sermorelin?

Take your Sermorelin injection daily at around the same time each day. Do not inject the drug any later than 12 hours after you have taken your last dose because it will not achieve optimal results. It is important to maintain a regular dosage schedule as irregular intakes can bring about serious health problems and could result in a complete lack of growth hormone (GH).

What are the side effects of Sermorelin?

Sermorelin has several positive benefits, but it is known to cause the following common side effects in some individuals:

* Headaches 

* Joint pain 

* Rigid muscles 

* Coughing up blood (rare)

These symptoms usually go away after a couple of days and do not require medical attention. Reporting these side effects to your doctor helps us monitor your treatment, modify it if needed and ensure that you receive the best possible care.

What is the normal dosage of Sermorelin?

Common dosage for Sermorelin

Common dosage for Sermorelin is typically between 1-2 IU per day. Your dose is determined by factors such as your age, weight and severity of low growth hormone. The maximum recommended dose is 4IU per day.

Product reviews for Sermorelin:

  1. Joshua Lucas (June 12, 2021): I started taking Sermorelin to treat delayed puberty. My doctor said that I would start seeing results within 6 to 12 months but the improvement in my muscle size and energy levels was noticeable after just 6 weeks. I feel much better now than I did when I was fifteen, which is good because my friends are all graduating college soon, so the next few years are going to be tough.
  2. Michael Smith (July 11, 2021): The daily injections suck but it’s worth it. Once you get past the initial discomfort of giving yourself a shot, what you get in return makes your efforts worthwhile – increased energy and focus during the day and incredible stamina at night! 
  3. Arthur Kelly (July 15, 2021): Sermorelin is the best, I’ve tried it all. It’s very versatile; you can use it to gain muscle mass or simply to reverse symptoms of aging/low growth hormone levels without the side effects associated with synthetic GH treatment (like insomnia). The best part is that Sermorelin works faster than HGH injections and costs less too!
  4. Ethan Mitchell (August 28, 2021): I have been taking Sermorelin for over two years now. I started using it after my checkup when my doctor told me that my growth hormone levels were low due to stress at work. Since starting this therapy, I have noticed a significant change in my energy levels and overall mood – no more mid-day naps!
  5. Eva Green (October 11, 2021): I started using Sermorelin after my yearly checkup. My doctor said that my growth hormone levels were low and recommended this treatment to me. At first, I was skeptical but now I’m so glad that I decided to try it – increased energy is just the tip of iceberg!
  6. Natalie Adams (October 13, 2021): If you want great results without having to go through painful injections for months on end then buy Sermorelin. It takes some time before you start seeing results but it’s definitely worth the wait! 
  7. Tara Ng (October 8, 2021): My ex-boyfriend introduced me to Sermorelin about two years ago and it’s honestly changed my life! I didn’t have any idea about synthetic growth hormone treatments before, but this is way better than taking HGH injections. It’s much cheaper, easier to use and it works faster too!
  8. Jenna Taylor (October 14, 2021): I tried Sermorelin after seeing the positive reviews online. At first, I didn’t think that it would work but now I can’t stop recommending this stuff to my friends! My energy levels are through the roof, and I feel great in general. The only side effect that freaks me out a bit are these weird dreams at night – they are really vivid sometimes – but other than that this is seriously the best medication ever!
  9. Ryan Lopez (October 24, 2021): I’ve been using Sermorelin for almost 10 months now and it’s been life changing. I started taking this stuff because of low energy levels, lack of focus during the day and my doctor said that it would only take a couple weeks to see results! It sounds too good to be true, but I have to say that even though the changes are small at first, they really add up over time.
  10. Jenny Adams (August 26, 2021): I’m a busy mom with 3 kids and a full-time job. Even though I’m always on the go I make sure to use Sermorelin because it has helped me feel better, both physically and mentally! Some people say that the side effects aren’t worth it but for me this treatment was a life changer!
  11. Matthew Cole (March 12, 2021): When my doctor told me about his experience with Sermorelin injections at first, I thought that it’s just another hyped up product by big pharma industry. After reading some reviews online and seeing how much cheaper this stuff is than HGH injections I decided to give it a try and after just one month of treatment I can already tell that my energy levels are through the roof again!
  12. Eva James (April 24, 2021): I’ve been using sermorelin for almost 4 months now and it’s the best thing that ever happened to me. My energy levels are through the roof, my workouts are more intense than ever before, I barely get sick anymore and even lost some weight because of increased focus! It definitely seemed too good to be true at first, but this treatment is legit! 
  13. Ana White (June 11, 2021): I started taking Sermorelin after seeing my doctor for a checkup. My growth hormone levels were low, but he was pretty sure that adding Sermorelin to my treatment plan would help with the symptoms of GH deficiency. After trying this stuff for over two years now – it’s fantastic! I can’t believe that there are still doctors who don’t know about this medication!
  14. Bryan Smith (July 23, 2021): Sermorelin is the best thing that ever happened to me. I started taking it after seeing my doctor for a routine checkup and he said that my growth hormone levels were low. After just one month of treatment with this stuff I already felt more energetic than before. It does take some time before you start seeing results but it’s totally worth it!
  15. Jill White (August 27, 2021): It took me about 2 weeks to see the first results from using Sermorelin but after that point I felt like a new person. My doctor told me that my growth hormone levels were low and that it would take time before they went up again. He wasn’t wrong at all; it does take some time but in my case it really got things going pretty fast!

 FAQ’s about Growth Hormone

Is Sermorelin Safe?

Many users have had great results with this medication and haven’t reported any side effects whatsoever which is why it’s considered one of the best treatments on the market today! However, some people have reported that they have experienced some mild side effects, but these are only temporary and will go away after you stop using Sermorelin. Of course, there are also some rare cases in which people have experienced some more severe Sermorelin side effects, but these are very rare, and no one has reported any case of death from using this medication.

How long will I be on Sermorelin?

Sermorelin usually starts working within a few weeks, after that it could take up until 4 weeks before seeing any improvement. This depends on how low your hormone levels when you started treatment. It’s recommended that this treatment is used for at least 6 months to see the best results!

Is Sermorelin right for me? 

Sermorelin is a safe and effective treatment for people who suffer from Growth Hormone Deficiency. However, if you have been diagnosed with a pituitary adenoma or any other condition which may make taking Sermorelin dangerous for your health consult with your doctor to see if this medication would be right for you! 

Where to buy Sermorelin? 

You can easily buy Sermorelin online and it will be shipped to you within a few days! That way you don’t even need to leave your home and we guarantee that we only provide the best quality products.

Can you take Sermorelin if you are underweight?

It’s not recommended to take Sermorelin if you are underweight because it may cause some side effects and, in the end, you won’t even notice any difference! Eating well and doing some exercise should help with this condition.

How long does a Sermorelin prescription last?

Once you have been treated with Sermorelin, your doctor will generally recommend an evaluation every six months to monitor your progress. In most cases, prescriptions for this medication are valid for up to 9 months but may vary depending on the severity of your condition and how quickly it is diagnosed and effectively treated. Your physician can alter dosage amounts or prescribe additional injections if necessary. However, once treatment has ended physicians generally do not recommend that patients revert to using GH therapy alone – especially if they had previously used synthetic GH in the past.

Who should not take Sermorelin?

There are certain individuals who should not use this medication. For instance, those under the age of 18 or those who have been diagnosed with a pituitary gland tumor or have experienced problems with their pituitary gland in the past should consult a health care professional before using Sermorelin. Pregnant and nursing women may also need to seek advice because scientists still don’t know if it’s safe for them to use the drug.

Sermorelin is totally worth trying out if you want to feel better again!

Sermorelin is a great and effective treatment for people who suffer from Growth Hormone Deficiency. It’s much safer than taking human growth hormone injections which can lead to some very serious health issues. We recommend that you start this treatment as soon as possible because the sooner you start it the better results you will see!

We hope you found this information useful. Remember that if you have any queries, please do not hesitate to ask them below!

Caffeine and Fat Burning

Do you drink coffee? More importantly, do you use coffee to help with your training or performance?

I know there are some people that can’t touch the stuff before training or it results in a trip to the bathroom mid-workout. Personally, I love to sip on a cup of coffee for an early morning workout for a bit of a boost.

But does it help? Specifically with respect to fat burning, does caffeine help? And does it make a difference what time of day you have a cup of coffee in relation to your training?

A recent study looked to answer this question. They wanted to know if caffeine would boost fat burning.

What they did was have the experiment subjects have a drink 30 minutes before an aerobic exercise workout. The subjects included 15 males averaging 32 years old. The subjects did 4 sessions 7 days apart. This allowed them to experience all 4 test conditions of coffee, placebo, 8 AM training or 5 PM training.

The researchers controlled for fasting, exercise and other stimulants consumed. They wanted to make sure the subjects weren’t doing workouts before coming to the lab or slamming back a Red Bull either.

The researchers used indirect calorimetry to measure maximal fat oxidation (MFO).

So what did they find?

MFO and VO2max were greater in the PM than in the AM.

When the groups consumed caffeine there was 10.7% greater MFO in the morning (i.e. 8 AM) compared to the group that consumed a placebo. And with the 5 PM group MFO was 29% greater when caffeine was consumed instead of a placebo.

So the two big takeaways are that:

  1. Caffeine works and helps increase MFO
  2. Results were better with the afternoon versus the morning group

A few things to keep in mind include:

  • Would we see the same results for different ages rather than everyone of approximately 32 years?
  • Would we see the same results for women?
  • Would we see the same results for sedentary individuals? All the participants in this study were already active.
  • Would the results have differed if more caffeine was consumed? The subjects consumed 3 mg/kg bodyweight. So an 80 kg individual would ingest 240 milligrams of caffeine. (a cup of coffee has about 100 mg)

Lastly, don’t lose sight of the fact that the best time to exercise is when you can make time for it. Different chronotypes do better at different times of day. And although afternoon caffeine resulted in more MFO compared to the morning don’t forget of the fat burning powers of sleep. If an afternoon cup of coffee disrupts sleep it may not be worth it.

Ramírez-Maldonado, M., Jurado-Fasoli, L., Del Coso, J., Ruiz, J. R., & Amaro-Gahete, F. J. (2021). Caffeine increases maximal fat oxidation during a graded exercise test: is there a diurnal variation?. Journal of the International Society of Sports Nutrition18(1), 1-9.

Obesity to Become Main Cancer Risk

Growing up we always associated smoking with cancer. We’d have the school assemblies to prevent us from lighting up. The packages of cigarettes had images of disgusting gum and tooth disease caused by smoking. And we all knew a relative or loved one that was a smoker and passed away from cancer.

That could all change.

Obesity could overtake smoking as the main cancer risk by 2040 in women and soon after in men.

And with the pandemic this isn’t getting any better. Since this time last year most people have put on a few pounds, are less active and eating more junk food. And when the food delivery services show up in our neighbourhood it’s usually bringing fast food. Combine this with more people quitting smoking and it’s easy to see how obesity will overtake smoking as a greater risk for cancer.

So what’s the big deal with obesity?

Well fat isn’t inert tissue that gets added to the body and has no effects. It doesn’t just sit there quietly but is active. It sends signals to other tissues and organs that affect growth, metabolism and reproductive processes.

When we are obese we are vulnerable to tissue damage and developing tumours. And there are least 12 types of cancer linked to carrying excess weight. Regular exercise is important for cancer prevention specifically breast and colon cancer.

A recent study in the UK involved exercising mice three times per week for 30 minutes. These mice showed lower levels of inflammation, which can lead to the development of tumours. As well, the mice that exercised improved their metabolism, had less fat in their livers and moved more quickly.

In the UK there are 135,000 new cancers per year (about 4 in 10) deemed to be preventable. Exercise can be a great way to reduced the chance of obesity and thus lessen the chance of developing cancer.

Bianchi, A., Marchetti, L., Hall, Z., Lemos, H., Vacca, M., Paish, H., & Wilson, C. L. (2021). Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. The Journal of Immunology206(4), 904-916.

Answers to all of your questions about creatine

After high school I remember training with my brother. And the goal wasn’t to improve performance in a sport. And it wasn’t to sprint faster. Or to rehab an injury.

It was purely for bodybuilding. We trained to get as big and strong as possible with more emphasis on the former.

And while we didn’t invest a dime into programming or coaching we always found it in the budget to have a tub of protein, some bars and creatine.

So while creatine has been available commercially to the average gym goer for over 30 years there are still a number of myths regarding this supplement. Some of the top supplement researchers and editors of the Journal of the International Society of Sports Medicine collaborated to put out a review of the more common questions that exist about creatine. The following is a brief summary of this review with the citation to follow.

Does creatine lead to water retention?

Researchers will distinguish between total body water (TBW), intracellular water (ICW) and extracellular water (ECW). Most studies do not show an increase in TBW. When loading creatine this is usually done at higher doses than during the maintenance phase and early research showed some water retention but didn’t distinguish between ICW and ECW.

The general understanding is that there is some evidence of water retention, primarily ICW, over the short term. Several studies show creatine doesn’t alter TBW (ICW or ECW) relative to muscle mass.

Does creatine damage the liver or kidneys?

After more than 20 years of research there are no adverse effects from taking the recommended dosage of creatine. Creatine and phosphocreatine are degraded to creatinine. The amount of creatinine in the blood is proportional to body mass and creatine intake.

There was a case study from the late 1990s when an individual did experience elevated levels of creatinine and usage was discontinued for this reason. Apparently this individual had previous renal/hepatic issues and was loading at 15 g per day. The case study makes no mention of the diet of the individual which can contribute to elevated levels of creatinine.

For healthy individuals, ingesting normal dosages, there are no known adverse effects for the kidneys or liver.

Does creatine cause dehydration or cramping?

During the loading phase of 20 g/ day for 5-7 days there may be an increase in body mass of 1-3 kg, which is mostly body water retention. The studies that do show dehydration/cramping don’t control for other supplements and beverages.

As well, a study looked at how many creatine users use the recommended daily dose and found 91% exceeded these amounts.

Another study had subjects put into two groups. 38 of them took creatine and another 34 took a placebo. Those that took creatine had less cramping, heat illness, dehydration, tightness, muscle strains and injuries.

And a study involving haemodialysis patients (n=10) that reported frequent cramping were given 12 grams of creatine before haemodialysis and saw a decreased frequency of cramping by 60%.

The take home message is the creatine does not appear in the research or anecdotally to result in cramping or dehydration.

Does creatine increase fat mass?

Whenever a substance is known to increase body mass, as creatine does, there may be concern for an increase in fat mass. This concern may be justified in that rarely do we add 100% muscle mass and zero fat mass when we increase our mass.

The literature is pretty clear and consistent on this however. There are numerous studies showing an increase in body mass, an increase in fat free mass yet no increase in fat mass. One study with swimmers showed no change in body composition.

A common criticism of the studies showing no increase in fat mass is that they are less than 8 weeks in duration and thus not long enough in duration to demonstrate a physiological change. There are more than enough studies greater than 8 weeks which show no significant change in fat mass.

Of interest was a study involving children with lymphoblastic leukemia. For 16 weeks some of the children received creatine and the others a placebo. Those taking creatine saw their fat mass decrease while those that didn’t take it saw an increase in their fat mass.

Supplementing with creatine may increase body mass without increasing fat mass.

Is a loading phase required?

If you’re familiar with using creatine as a supplement you’ll know there’s something called a ‘loading’ and a ‘maintenance’ phase. The loading phase involves taking creatine at 20-25 grams per day for 5 to 7 days to saturate the muscle. Once the loading phase is complete then the maintenance phase follows at doses of 3-5 grams per day.

A study compared loading versus simply going to the maintenance phase and determined that both resulted in an increase of muscle creatine concentrations by 20%. Loading speeds up the process but doesn’t add any additional benefits. Going straight to a loading phase delays but doesn’t limit the benefits of using creatine when used for at least four weeks.

When an athlete is looking to benefit from creatine in a short period of time i.e. less than 3 weeks, than a loading protocol would be preferred. If creatine will be used for a longer duration i.e. at least four weeks, than it would be fine to go straight to a maintenance phase, especially if avoiding or minimizing the increase in body mass is desirable.

Is creatine just for power or resistance athletes?

We know that creatine is a phosphagen and helps supply and replenish cellular energy for short burst, high intensity activities. So typically it has been sought out by athletes that need to display high levels of force in a short period of time. This would include sprinting, jumping, throwing and kicking among other actions.

But does creatine help other athletes and functions?

There is growing evidnce to suggest that it is. For example, when creatine is taken with carbohydrate or carbohydrate with protein there is greater glycogen storage compared to carbohydrate alone. Glycogen is the form of carbohydrate that we store in the muscle and liver and is important for training and recovery.

Those that supplement with creatine show less muscle damage and in a four week study with runners training up to 30 km those taking creatine experienced less muscular damage, inflammation and soreness.

Lastly, creatine appears to offer protective benefits to the brain and spinal cord and may be a good idea for those in collision sports and at risk for concussion.

Creatine offers many benefits and need not be limited to only those in power or resistance sports.

Below is a summary of each of the sections of the review. For more details and to read the sections not covered above see the citation below. The section below in italics is copied directly from the review.

Based on our evidence-based scientific evaluation of the literature, we conclude that:

  1. Creatine supplementation does not always lead to water retention.
  2. Creatine is not an anabolic steroid.
  3. Creatine supplementation, when ingested at recommended dosages, does not result in kidney damage and/or renal dysfunction in healthy individuals.
  4. The majority of available evidence does not support a link between creatine supplementation and hair loss / baldness.
  5. Creatine supplementation does not cause dehydration or muscle cramping.
  6. Creatine supplementation appears to be generally safe and potentially beneficial for children and adolescents.
  7. Creatine supplementation does not increase fat mass.
  8. Smaller, daily dosages of creatine supplementation (3-5 g or 0.1 g/kg of body mass) are effective. Therefore, a creatine ‘loading’ phase is not required.
  9. Creatine supplementation and resistance training produces the vast majority of musculoskeletal and performance benefits in older adults. Creatine supplementation alone can provide some muscle and performance benefits for older adults.
  10. Creatine supplementation can be beneficial for a variety of athletic and sporting activities.
  11. Creatine supplementation provides a variety of benefits for females across their lifespan.
  12. Other forms of creatine are not superior to creatine monohydrate.

Antonio J., Candow D.G., Forbes S.C., Gualano B., Ragim A.R., Kreider R.N., Rawson E.S., Smith-Ryan A.E., VanDusseldorp T.A., Willoughby D.S. & Ziegenfuss T.N. (2021). Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? Journal of the International Society of Sports Nutrition, 18(13).

MOTS-c – The Fountain of Youth Protein

When I think of longevity a couple of movies come to mind. Cocoon and The Curious Case of Benjamin Button cover this theme in different ways.

Or a quick history lesson takes us back to Ponce de Leon and the search for the fountain of youth.

Researchers at USC may have found the protein that confers anti-aging benefits.

The protein is MOTS-c and is a mitochondrial protein. Mitochonria can thought of as the powerhouse of the cell and are responsible much of our cellular energy. MOTS-c acts by heping promote metabolism amd maintaining homeostasis.

Previous research into MOTS-c has shown that it helps increase insulin
sensitivty and reverse obesity in mice.

In human when we exercise we see the level of MOTS-c is elevated almost 12x and remains elevated for up to four hours post-exercise.

What the research team at USC did was inject MOTS-c into mice of various ages and then measure their speed and agility, among other things. For mice, young is considered 2 months old, 12 months is middle age and old is 22 months.

The researchers injected the mice three times per week and had them perform a running test. The mice would warm-up for 5 minutes at 13 metres per minute. After five minutes the speed was increased one metre per minute for five minutes to reach 18 metres per minute. The mice then ran for up to 30 minutes at a top speed of 23 metres per minute.

What they found is the older mice i.e. 22 months old, were able to keep up and outrun the young and middle aged mice. As well, the older mice were more sure-footed compared to the younger mice.

This is encouraging and it appears MOTS-c may play a role in healthy aging. It helped with the metabolic fitness and physical capacity of the mice in this study. And MOTS-c was also able to reverse diet induced obesity and insulin resistance in mice as well.

While we shouldn’t expect the same results in humans as in mice this is more support regarding the importance of maintaining fitness and training as we age. This will not only allow us to have more years but a better quality of life with the years we add.

Reynolds, J. C., Lai, R. W., Woodhead, J. S., Joly, J. H., Mitchell, C. J., Cameron-Smith, D., & Lee, C. (2021). MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nature Communications12(1), 1-11.